News Releases about:
Auxilium makers of AA4500 (collagenase)
Here is, apparently, a recent PowerPoint from
Auxilium makers of AA4500 (collagenase), that answers some
questions, sort of. This drug is going through FDA trials as a
means of remolding scar tissue in at least a few different conditions
including Peyronies Disease
Once on this site, the AA4500 presentatin slides pretty far down the page. Note the proposed
timeline showing AA4500 being marketed in 2008-9. Often investor
presentations are overly optimistic. Other interesting points:
they claim verapamil is "ineffective" ,that surgery is the only
"approved" treatment for Dupuytren's (not true) - and, that AA4500 has
worked on Peyronie's. Their initial level II trials used 9 injections
and they hope to reduce that number in their IIb trials.
May 22, 2006
Cook Features Surgisis ES: New Product
for the Treatment of Penile Curvature; Surgisis ES Featured at Atlanta
Cook Urological today announced that it will
highlight a new product, Surgisis(R) ES(TM), for the treatment of
The surgical treatment to correct penile
curvature utilizes Surgisis ES, a natural biomaterial that provides a
graft that is strong, easy to handle, easy to use, biocompatible and
supports the growth of new fully-vascularized host tissue in the penis.
Results of research conducted by Dr. L Dean Knoll at the Center for
Urological Treatment in Nashville Tennessee showed that penile curvature
was surgically corrected with the Surgisis ES graft in 90 percent of the
cases studied. Dr. Knoll's study also reported no incidence of penile
shortening, pain, infection, hematoma, bulging at the graft site or
evidence of a local immunogenic reaction. His study concludes that the
ease of handling and surgically placing the Surgisis ES graft combined
with no comorbidities from tissue harvesting techniques, coupled with no
adverse reactions make Surgisis ES an anatomic and functional tunical
Surgisis ES is made from Cook Biotech's Small
Intestinal Submucosa (SIS) technology, a breakthrough innovation for the
reinforcement or repair of damaged tissue. SIS is made from the porcine
small intestine and is processed to produce a three-dimensional
extracellular matrix (ECM) consisting of collagen, non-collagenous
proteins and biomolecules.
The SIS graft results in site-specific tissue
remodeling, called "smart tissue remodeling," which takes place when the
host and the graft become indistinguishable. While synthetic or
cross-linked implants can encapsulate and form a barrier to the body's
natural defenses, SIS grafts are rapidly infiltrated by the host cells,
tissues and blood vessels, becoming accessible to the host immune
Cook Urological and Women's Health Gail
McDaniel, 1-812-829-4891 ext. 7067 firstname.lastname@example.org or
Racepoint Group Dan Carter, 781-487-4602 email@example.com
to this website
The Peyronies Disease Society (formerly "Peyronies Disease Patient
Discussion Forum") has reorganized as an organization geared toward
greater understanding of this disease. This announcement is yet to be
released in the Peyronie's Disease community, including our hundreds of
members, pending further development of this site.
Our goal is to support
patients, make the general public aware of this disease with its impact
on individuals and society, to act as liaison with researchers, to
provide an patient resource for physician interaction, and for the
mutual education of us all.
Our Society makes a public announcement of our new name and our new
We Added the page
Evidence. This is directed at helping patients more accurately
evaluate treatment claims and evaluate medical studies. This page
links off of all the treatment pages.
We added a site Map that shows the
entire site layout and includes links to every page.
The survey on
intra-lesional verapamil was opened to all website visitors (ILV).
Results will be posted on this website at a later time.
A basic Peyronies Disease
Glossary was added and linked to from our
"The Disease" page. This will be expanded over time.
The first exclusive Women only Forum for women impacted by Peyronie's
Disease went online on a private board off of our main Peyronie's Forum.
We also published a new web page giving an over view of the problems
women often face from Peyronie's Disease and ways the new
Women's Peyronies Forum attemps to help.
An excellent article on
Intimacy and Sexuality was contributed by one
of our members and published as a web page. An expanded version
with other member contributions will soon be available on the Peyronies
Disease Society Forum.